GRIDHAPLO: A grid package for Genome Wide Haplotype Association Study (GWHAS).
GridHaplo implements a sliding windows haplotype analysis approach for
analyzing GWAS SNP data set as described in Tregouet et al. GridHaplo is still under development but its beta version is available for download.
A new JAVA interface implementation of THESIAS: testing haplotype effects in association studies
THESIAS is a popular software for carrying haplotype association analysis in unrelated individuals. In addition to the command line interface, a graphical JAVA interface is now proposed allowing one to run THESIAS in an user-friendly manner. Besides, new functionalities have been added to THESIAS including the possibility to analyse polychotomous phenotype and X-linked polymorphisms.
DICE in Genetic Association Studies of Complex Traits
Approaching complex diseases by studying one or a few genetic polymorphisms has shown its limitations. It is now increasingly recognized that understanding the genetic basis of complex phenotypes requires not only to investigate all polymorphisms located in functional regions of candidate genes but also to integrate information about the network of genes involved in biological systems of major physiological importance, such as lipid metabolism, cellular adhesion, inflammation...
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